sci chem cause cure

These reports of background DNA damage had a dramatic effect on carcinogenesis research. Attention shifted from exogenous compounds as the sole source of DNA damaging agents to endogenous compounds. The ease with which 8-oxo-dG could be measured in tissues, body fluids, etc. rapidly led to hundreds of reports of its detection in animal and human DNA. Had Science magazine initiated its `molecule of the year' feature in the late 1980s, a strong case could have been made for 8-oxo-dG.